CHICAGO – October 19, 2023 – People who test positive for BRCA1/2 genetic variants may be at risk for other types of cancer beyond those previously known, according to a study being presented at the National Society of Genetic Counselors (NSGC) 42nd Annual Conference.
People with pathogenic/likely pathogenic (P/LP) BRCA1 or BRCA2 (BRCA1/2) variants are known to be at increased risk for “core” cancers: breast, ovarian, prostate, pancreatic, and melanoma. The new research found people with P/LP BRCA1/2 variants also had significantly higher rates of endometrial, esophageal, gastric, testicular and urinary tract cancers compared to those who did not have such variants.